Utility of the modified ATP III defined metabolic syndrome and severe obesity as predictors of insulin resistance in overweight children and adolescents: a cross-sectional study

Table 2 Using Metabolic Syndrome or Severe Obesity to Predict Higher Insulin Resistance*

Predictor	n^†	OR (95% CI)	p	Sensitivity^‡	Specificity	PPV
Metabolic Syndrome
Ages 3–8	55	1.3 (0.6, 2.7)	.70	49%	57%	36%
9–11	79	1.4 (0.7, 2.7)	.41	54%	55%	37%
12–19	123	2.0 (1.2, 3.4)	.006	54%	63%	42%
Severe Obesity
Ages 3–8	80	0.9 (0.4, 1.9)	.88	63%	33%	33%
9–11	65	3.0 (1.5, 5.9)	.002	57%	69%	48%
12–19	116	2.0 (1.2, 3.3)	.01	51%	66%	51%

*Metabolic syndrome (MetS) by modified ATP III criteria; higher insulin resistance: upper tertile of homeostatis model (HOMA); severe obesity: BMI Z score ≥ 2.5.
^† n = number in age group with MetS or severe obesity respectively; OR (95%CI): Odds ratio and 95^% confidence interval.
^‡ Sensitivity: % of those with higher insulin resistance who have predictor. Specificity: % of those without predictor who do not have higher insulin resistance. Positive predictive value (PPV): % of those with predictor who have higher insulin resistance.

ISSN: 1475-2840