Time course of glucose levels after ICU admission. Comparison of post-cardiac surgery hyperglycemia for the single dose group (1D group, triangles, 116 patients) and for the double dose group (2D group, circles, 158 patients). Data are medians and interquartile ranges. The glucose level was higher at 4, 6, 9, 12, and 24 hours in the 2D group (all p < 0.001, after Bonferroni correction for multiple testing). The difference was largest at 12 hours after ICU admission.