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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions

Figure 3

Effect of TZDs on the induction of thymidine kinase assessed by acute [3H]-thymidine uptake and parallel estimation of [3H]-thymidine incorporation into DNA. A. Confluent serum deprived vSMCs were treated with PDGF with and without troglitazone for 20 h then cells were washed free and growth factor and drugs and the acute uptake of [3H]-thymidine over 4 min was assessed. The results show the effects of two identical experiments in duplicate. B. Shows concomitant data for routine assay of [3H]-thymidine into DNA (see methods for details).

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Cardiovascular Diabetology

ISSN: 1475-2840