Study | DREAM [94] (Rosiglitazone) | STOP-NIDDM [7,20] (Acarbose) | DPP [5,48] |
---|---|---|---|
Patient population | IGT/IFG n = 5269 | IGT n = 1368 | IGT n = 2155 |
Effect of intervention on diabetes incidence | -60% (p < 0.0001) | -36.4% (p = 0.003) | -31% (p < 0.01) |
Effect of intervention on new hypertension incidence | n/a | -34% (p = 0.006) | +25% (not significant) |
Effect of intervention on rate of predefined CV events | +37% (p = 0.08) | -49% (p = 0.03) | n/a |