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Table 2 Clinical characteristics and metabolic parameters of female subjects with type-2 diabetes, pre-diabetes and healthy control subjects

From: Serum leptin and its relation to anthropometric measures of obesity in pre-diabetic Saudis

 

No diabetes

Pre-diabetes

Type-2 diabetes

N

35

37

45

Age (years)

43.6(11.3)

43.3(11.7)

49.0(12.6)d

Systolic blood pressure (mm Hg)

122.8(23.1)

127.3(24.2)

123.6(18.6)

Diastolic blood pressure (mm Hg)

79.4(16.5)

79.8(8.03)

80.7(10.3)

BMI (kg/m2)

30.4(6.4)

32.5(8.4)

32.5(10.3)

Waist (cm)

90.5(12.5)

91.8(13.5)

96.2(17.9)

Hips (cm)

105.3(14.1)

104.8(17.9)

106.7(20.8)

Fasting Glucose (mmol/L)

4.8(0.9)

6.1(0.4)b

14.1(5.5)b

Cholesterol (mmol/L)

5.2(1.3)

5.3(1.1)

6.6(1.9)b

HDL (mmol/L)

1.1(0.4)

0.9(0.4)

1.1(0.3)

Triglyceride (mmol/L)

1.9(1.9)

1.6(0.9)

2.6(1.4)

LDL (mmol/L)

3.5(1.4)

3.6(1.1)d

4.4(1.5)c

Insulin (μmol/L)*

15.2(2–62)

13.5(6–26)

14.04(1–52)

Leptin ng/mL *

10.2(0.25–34.8)

14.09(2.8–44.4)a

13.3(3.6–49.1)

APO A1 mg/dL

0.8(0.4)

0.9(0.4)

1.2(2.5)

APO A11 mg/dL

0.4(0.1)

0.4(0.1)

0.4(0.2)

HOMA IR *

3.1(0.3–12.5)

3.6(1.5–7.3)

7.8(0.6–28.4)b

  1. *Data are presented as means (SD) or as medians (interquartile range) for insulin, leptin and HOMA-IR data. The P-values shown are comparisons of metabolic characteristics for case control versus either prediabetics or patients with T2DM: a) 0.046; b) p = 0.03; c) p = 0.004; d) p < 0.001