Skip to main content
Figure 3 | Cardiovascular Diabetology

Figure 3

From: Diabetes alters vascular mechanotransduction: pressure-induced regulation of mitogen activated protein kinases in the rat inferior vena cava

Figure 3

Diabetes related alterations in loading-induced p38-MAPK phosphorylation in the IVC are isoform-specific. The basal (control) and pressure-induced phosphorylation of the p38-MAPK in venae cavae from non-diabetic lean Zucker (LNZ) and diabetic obese syndrome X Zucker (OSXZ) rats. Phosphorylation status of A.) p38γ-MAPK, B.) p38α-MAPK, and C.) p38β-MAPK was calculated as phosphospecific optical density divided by the unpressurized non-diabetic control value. * Significantly different from unloaded venae cavae within the same group (P < 0.05). † Significantly different from corresponding non-diabetic venae cavae (P < 0.05). n = 6/group.

Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840