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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes

Figure 3

Influence of metformin on IL-6 release and inhibiton of HMW-APM stimulated IL-6 by a NFκB inhibitor. (A) Monocytes from 3 controls were cultivated with 0.5 mM metformin for 24 h and IL-6 was determined. (B) Monocytes from 2 different donors were incubated with 10 μg/ml HMW-APM alone or in combination with 2.5, 5.0 or 10.0 μM InSolution™ NF-κB Activation Inhibitor for 24 h and IL-6 was measured.

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Cardiovascular Diabetology

ISSN: 1475-2840