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Table 3 Genes that were modulated by oxidized LDL concomitantly with the genes of the insulin signaling cascade in hyperinsulinemic hyperglycemic conditions.

From: Insulin and glucose play a role in foam cell formation and function

  Mean absolute intensity     
Description Vehicle mmLDL OxLDL Fold change: OxLDL vs. Vehicle Fold change: MmLDL vs. Vehicle P: OxLDL vs. Vehicle P: MmLDL vs. Vehicle
Phospholipase A2 (PLA2G4C) 455.5 266.0 509.0 1.1 -1.7 N.S.* <0.0005
5-lipoxygenase activating protein (ALOX5AP) 1583.3 2249.3 1160.0 -1.4 1.4 <0.05 <0.01
Leukotriene A 4 hydrolase (LTA4H) 3156.8 3751.3 3743.6 1.2 1.2 N.S. N.S.
  1. *) N.S. – not statistically significant (p > 0.05).