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Table 3 Genes that were modulated by oxidized LDL concomitantly with the genes of the insulin signaling cascade in hyperinsulinemic hyperglycemic conditions.

From: Insulin and glucose play a role in foam cell formation and function

 

Mean absolute intensity

    

Description

Vehicle

mmLDL

OxLDL

Fold change: OxLDL vs. Vehicle

Fold change: MmLDL vs. Vehicle

P: OxLDL vs. Vehicle

P: MmLDL vs. Vehicle

Phospholipase A2 (PLA2G4C)

455.5

266.0

509.0

1.1

-1.7

N.S.*

<0.0005

5-lipoxygenase activating protein (ALOX5AP)

1583.3

2249.3

1160.0

-1.4

1.4

<0.05

<0.01

Leukotriene A 4 hydrolase (LTA4H)

3156.8

3751.3

3743.6

1.2

1.2

N.S.

N.S.

  1. *) N.S. – not statistically significant (p > 0.05).