Table 1 Distribution of various atherosclerotic risk factors and inflammation markers, specified by steatohepatitis, fatty liver and normal control groups
| Â | Â | Â | Steatohepatitis | N = 124 | Â | Â | Fatty liver only | N = 124 | Â | Â | Normal | N = 124 | P value* | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | Std | median | Â | Q1 | Â | Q3 | Â | Mean | Std | median | Â | Q1 | Â | Q3 | Â | Mean | Std | median | Â | Q1 | Â | Q3 | Â | Â | |
Age (years) | 49.7 ± | 11.0 | 49 | ( | 42 | - | 57 | ) | 49.8 ± | 10.6 | 49 | ( | 43 | - | 57 | ) | 49.5 ± | 11.9 | 49 | ( | 43 | - | 57 | ) | 0.970 |
Weight (kg) | 77.0 ± | 11.4 | 75 | ( | 70 | - | 83 | ) | 71.5 ± | 10.0 | 72 | ( | 65 | - | 78 | ) | 65.0 ± | 9.5 | 65 | ( | 58 | - | 72 | ) | <.0001 |
BMI (kg/m2) | 27.6 ± | 3.1 | 27 | ( | 25 | - | 29 | ) | 25.5 ± | 2.7 | 26 | ( | 24 | - | 27 | ) | 23.4 ± | 2.7 | 23 | ( | 22 | - | 25 | ) | <.0001 |
Fasting glucose (mg/dL) | 107.9 ± | 29.5 | 98 | ( | 89 | - | 117 | ) | 100.1 ± | 27.3 | 92 | ( | 87 | - | 101 | ) | 92.9 ± | 20.8 | 89 | ( | 84 | - | 95 | ) | <.0001 |
HDL-cholesterol (mg/dL) | 42.4 ± | 9.2 | 41 | ( | 36 | - | 48 | ) | 44.9 ± | 10.9 | 43 | ( | 38 | - | 49 | ) | 50.9 ± | 11.9 | 50 | ( | 43 | - | 58 | ) | <.0001 |
Triglyceride (mg/dL) | 195.9 ± | 89.5 | 176 | ( | 130 | - | 256 | ) | 166.6 ± | 86.0 | 146 | ( | 115 | - | 201 | ) | 107.4 ± | 51.7 | 96 | ( | 70 | - | 136 | ) | <.0001 |
Systolic blood pressure (mmHg)** | 127.9 ± | 13.9 | 126 | ( | 119 | - | 137 | ) | 124.5 ± | 15.0 | 123 | ( | 116 | - | 128 | ) | 120.8 ± | 13.6 | 120 | ( | 110 | - | 128 | ) | <.0001 |
Diastolic blood pressure (mmHg)** | 80.7 ± | 9.8 | 80 | ( | 74 | - | 87 | ) | 77.4 ± | 11.7 | 78 | ( | 71 | - | 83 | ) | 74.0 ± | 11.8 | 73 | ( | 68 | - | 82 | ) | <.0001 |
Total cholesterol (mg/dL) | 202.4 ± | 36.0 | 204 | ( | 183 | - | 229 | ) | 200.3 ± | 33.1 | 197 | ( | 181 | - | 217 | ) | 184.4 ± | 35.1 | 182 | ( | 159 | - | 206 | ) | <.0001 |
LDL-cholesterol (mg/dL) | 121.3 ± | 30.9 | 119 | ( | 102 | - | 143 | ) | 122.1 ± | 32.2 | 119 | ( | 105 | - | 136 | ) | 106.9 ± | 29.8 | 101 | ( | 84 | - | 125 | ) | <.0001 |
White Blood Cell (/μL) | 6920 ± | 1525 | 6745 | ( | 5920 | - | 7960 | ) | 6780 ± | 1685 | 6555 | ( | 5665 | - | 7685 | ) | 6471 ± | 1563 | 6195 | ( | 5360 | - | 7900 | ) | 0.071 |
Lymphocyte (/μL) | 2488 ± | 693 | 2442 | ( | 2065 | - | 2843 | ) | 2384 ± | 660 | 2238 | ( | 1943 | - | 2753 | ) | 2233 ± | 765 | 2109 | ( | 1674 | - | 2691 | ) | 0.002 |
Neutrophils (/μL) | 3656 ± | 1134 | 3557 | ( | 2898 | - | 4445 | ) | 3621 ± | 1208 | 3420 | ( | 2671 | - | 4186 | ) | 3481 ± | 1096 | 3268 | ( | 2658 | - | 4183 | ) | 0.371 |
C-reactive protein (mg/dL) | 0.33 ± | 0.39 | 0.24 | ( | 0.14 | - | 0.37 | ) | 0.26 ± | 0.27 | 0.17 | ( | 0.05 | - | 0.31 | ) | 0.21 ± | 0.32 | 0.14 | ( | 0.05 | - | 0.25 | ) | <.0001 |
Framingham score | 10.9 ± | 5.1 | 11 | ( | 8 | - | 15 | ) | 9.6 ± | 5.1 | 10 | ( | 7 | - | 13 | ) | 8.5 ± | 5.8 | 10 | ( | 7 | - | 12 | ) | 0.006 |
Framingham risk | 9.4 ± | 8.6 | 6 | ( | 3 | - | 12 | ) | 7.4 ± | 7.2 | 5 | ( | 2 | - | 10 | ) | 6.3 ± | 6.2 | 4.5 | ( | 1 | - | 8 | ) | 0.009 |
Smoking amount (pack*year) | 9.7 ± | 18.0 | 0 | ( | 0 | - | 16 | ) | 5.9 ± | 20.2 | 0 | ( | 0 | - | 3 | ) | 8.2 ± | 15.6 | 0 | ( | 0 | - | 12.5 | ) | 0.043 |
HbA1c (%) | 5.9 ± | 1.2 | 5.6 | ( | 5.2 | - | 6.1 | ) | 5.6 ± | 0.9 | 5.4 | ( | 5.1 | - | 5.8 | ) | 5.3 ± | 0.7 | 5.1 | ( | 5.0 | - | 5.4 | ) | <.0001 |