Table 3 Percentage change from baseline in lipid variables at 4 weeks (ITT population)
Variable | Least-squares mean percentage change from baseline to 4 weeks | Difference (95% CI) | p-value | |
|---|---|---|---|---|
Rosuvastatin 10 mg (n = 232) | Atorvastatin 10 mg (n = 231) | |||
LDL-C | -47.6 | -38.5a | -9.1 (-11.4, -6.7) | < 0.0001 |
TC | -33.6 | -27.9 | -5.7 (-7.4, -4.0) | < 0.0001 |
HDL-C | 4.4 | 2.6 | 1.8 (-0.5, 4.0) | NS |
TG | -19.2 | -15.5 | -3.7 (-9.5, 2.2) | NS |
Non-HDL-C | -42.6 | -35.0 | -7.6 (-9.6, -5.7) | < 0.0001 |
LDL-C/HDL-C ratio | -49.3 | -39.5 | -9.8 (-12.2, -7.4) | < 0.0001 |
Non-HDL-C/HDL-C ratio | -44.4 | -35.9 | -8.5 (-10.8, -6.2) | < 0.0001 |
TC/HDL-C ratio | -35.8 | -29.0 | -6.7 (-8.7, -4.8) | < 0.0001 |
Apo B | -42.9 | -35.3 | -7.6 (-9.7, -5.6) | < 0.0001 |
Apo A-I | 2.6 | 0.8 | 1.8 (0, 3.5) | 0.05 |
Apo B/apo A-I ratio | -43.9 | -35.4 | -8.5 (-10.6, -6.4) | < 0.0001 |