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Figure 6 | Cardiovascular Diabetology

Figure 6

From: Vascular ossification – calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis – calcific uremic arteriolopathy: the emerging role of sodium thiosulfate

Figure 6

Sensitizers and the Cbfa-1 "protein switch" to transform mesenchymal cells into osteroblast-like cells. This slide demonstrates the transformation of the pluripotent mesenchymal VSMC and pericyte into an osteoblast-like cell. It reveals the importance of the ossification sensitizers and core binding factor alpha-1 Cbfa-1 emphasizing their important role in VOC.

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