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Table 4 Multivariate associations of risk factors with PAD

From: Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes

Dependent variable Independent variable Unit OR (95% CI) P
PAD, left or right MTHFR 677C>T 677C/T 3.54 (1.01, 12.4) 0.049
  oral treatment for diabetes + 0.31 (0.082, 1.20) NS (0.091)
  current smoker + 3.04 (0.82, 11.2) NS (0.095)
  hypertension + 2.58 (0.58, 11.6) NS (0.22)
  age 10 yr 1.36 (0.80, 2.29) NS (0.26)
  duration of diabetes 5 yr 0.79 (0.45, 1.38) NS (0.41)
  insulin administration + 0.96 (0.18, 5.08) NS (0.97)
  sex male 1.00 (0.30, 3.34) NS (0.99)
  1. Hypertension: systolic blood pressure ≥ 130 and/or diastolic blood pressure ≥ 80 and/or antihypertensive treatment.
  2. Abbreviations: OR, odds ratio; PAD, peripheral arterial disease; MTHFR, methylenetetrahydrofolate reductase; NS, not significant.