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Table 3 PAD and intermittent claudication according to MTHFR 677C>T genotype

From: Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes

  677C/C n = 108 677C/T n = 30 OR (95% CI) P*
PAD, left or right (n, %) 12 (11.1%) 8 (26.7%) 2.91 (1.06, 7.97) 0.042
   PAD, left (n, %) 7 (6.48%) 4 (13.3%) 2.22 (0.60, 8.16) NS (0.25)
   PAD, right (n, %) 9 (8.33%) 7 (23.3%) 3.35 (1.13, 9.93) 0.047
Intermittent claudication (n, %) 6 (5.56%) 2 (6.67%) 1.20 (0.26, 5.64) NS (0.68)
  1. * Fisher's exact test
  2. Abbreviations: OR, odds ratio; PAD, peripheral arterial disease; NS, not significant.