| |
N
|
677C/C
|
677C/T
|
P
|
|---|
|
N (men/women)
|
138
|
108 (41/67)
|
30 (8/22)
|
NS (0.25)
|
|
Age (years)
|
138
|
46.4 ± 11.1
|
45.1 ± 13.5
|
NS (0.60)
|
|
BMI (kg/m2)
|
137
|
29.7 ± 4.7
|
32.6 ± 5.5
|
0.0050
|
|
Waist circumference (cm)
|
137
|
103 ± 9
|
106 ± 11
|
NS (0.063)
|
|
Current smoker (%)
|
138
|
50.0
|
50.0
|
NS (1.00)
|
|
Duration of diabetes (years)
|
138
|
8.53 ± 6.35
|
9.20 ± 7.01
|
NS (0.62)
|
|
Fasting glucose (mmol/L)
|
130
|
10.20 ± 3.91
|
9.28 ± 3.03
|
NS (0.33)
|
|
HbA1c (%)
|
136
|
8.36 ± 2.25
|
8.66 ± 2.18
|
NS (0.47)
|
|
Total cholesterol (mmol/L)
|
133
|
4.91 ± 1.07
|
4.67 ± 0.82
|
NS (0.27)
|
|
HDL-C (mmol/L)
|
133
|
1.21 ± 0.29
|
1.21 ± 0.29
|
NS (0.91)
|
|
LDL-C (mmol/L)
|
130
|
2.75 ± 0.71
|
2.70 ± 0.67
|
NS (0.78)
|
|
Plasma triglycerides (mmol/L)
|
133
|
2.20 ± 2.78
|
1.66 ± 0.60
|
NS (0.15)
|
|
Systolic BP (mmHg)
|
138
|
123 ± 16
|
132 ± 22
|
0.021
|
|
Diastolic BP (mmHg)
|
138
|
73.9 ± 8.9
|
77.4 ± 9.4
|
NS (0.077)
|
|
Hypertensive (%)
|
138
|
62.0
|
66.7
|
NS (0.64)
|
|
CRP (mg/L)
|
133
|
4.91 ± 6.65
|
6.53 ± 8.37
|
NS (0.19)
|
|
ABI, left
|
138
|
1.08 ± 0.09
|
1.05 ± 0.12
|
NS (0.26)
|
|
ABI, right
|
138
|
1.08 ± 0.09
|
1.07 ± 0.13
|
NS (0.73)
|
- Data are means ± s.d., unless otherwise indicated.
- Hypertension: systolic BP ≥ 130 and/or diastolic BP ≥ 80 and/or antihypertensive treatment
- Abbreviations: BMI, body mass index; HbA1c, glycosylated hemoglobin; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; BP, blood pressure; CRP, C-reactive protein; ABI, ankle-brachial index; NS, not significant.
