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Table 1 Characteristics of Oji-Cree type 2 diabetic patients according to the presence or absence of PAD (max n = 138)

From: Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes

  PAD present PAD absent P
  N   N   
Sex (% male) 20 35.0 118 35.6 NS (0.96)
Age (years) 20 48.0 ± 11.2 118 45.8 ± 11.7 NS (0.44)
BMI (kg/m2) 20 30.4 ± 5.7 117 30.3 ± 4.9 NS (0.98)
Waist circumference (cm) 20 102 ± 13 117 104 ± 9 NS (0.52)
Current smokers (%) 20 65.0 118 47.5 NS (0.15)
Duration of diabetes (years) 20 8.70 ± 4.64 118 8.67 ± 6.76 NS (0.98)
Insulin treatment (%) 16 25.0 98 18.4 NS (0.51)
Intake of antidiabetic drugs (%) 16 31.3 98 58.2 0.045
Taking lipid medication (%) 20 5.0 118 16.1 NS (0.31)
Fasting glucose (mmol/L) 19 10.27 ± 2.79 111 9.96 ± 3.90 NS (0.48)
HbA1c (%) 20 8.30 ± 1.93 116 8.44 ± 2.29 NS (0.92)
Total cholesterol (mmol/L) 19 4.43 ± 0.63 114 4.93 ± 1.06 0.036
Plasma triglycerides (mmol/L) 19 1.54 ± 0.60 114 2.18 ± 2.68 NS (0.059)
Systolic BP (mmHg) 20 136 ± 21 118 123 ± 16 0.0028
Diastolic BP (mmHg) 20 74 ± 10 118 75 ± 9 NS (0.81)
Hypertensive (%) 20 70.0 118 61.9 NS (0.49)
CRP (mg/L) 19 6.86 ± 12.0 114 4.97 ± 5.87 NS (0.99)
ABI, left 20 0.96 ± 0.12 118 1.09 ± 0.08 <0.0001
ABI, right 20 0.93 ± 0.06 118 1.10 ± 0.08 <0.0001
Intermittent claudication (%) 20 15.0 118 4.2 NS (0.091)
  1. Data are means ± s.d., unless otherwise indicated.
  2. PAD, peripheral arterial disease: ABI <0.95; Hypertension: systolic BP ≥ 130 and/or diastolic BP ≥ 80 and/or antihypertensive treatment.
  3. Abbreviations: BMI, body mass index; HbA1c, glycosylated hemoglobin; BP, blood pressure; CRP, C-reactive protein; ABI, ankle-brachial index; NS, not significant.