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Table 4 Baseline fasting biochemistry for the 9795 randomized participants in the FIELD study

From: Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]

Parameter

Baseline

After 6 weeks of fenofibrate||

Mean

SD

Median

Q1, Q3

Mean

SD

Total cholesterol (mmol/L)

5.04*

0.69

5.03*

4.56, 5.54

4.49

0.69

HDL cholesterol (mmol/L)¶

1.10*

0.26

1.06*

0.92, 1.24

1.16

0.29

Calculated LDL cholesterol (mmol/L)

3.07*

0.64

3.08*

2.62, 3.51

2.71

0.62

Triglycerides (mmol/L)

1.94*

0.88

1.74*

1.34, 2.34

1.37

0.63

Total-to-HDL cholesterol ratio

4.81*

1.10

4.71*

4.04, 5.49

4.08

1.13

Apolipoprotein B (g/L)

0.97*

0.17

0.97*

0.86, 1.09

0.83

0.18

Creatinine (mmol/L)

0.08†

0.02

0.08†

0.07, 0.09

0.09

0.02

Fibrinogen (g/L)

3.6†

0.8

3.6†

3.1, 4.1

3.12

0.75

Fasting glucose (mmol/L)

8.9†

2.6

8.5†

7.0, 10.3

--

--

Urinary albumin-to-creatinine ratio (mg/mmol)

5.9†

21.8

1.2†

0.7, 3.0

--

--

Homocysteine (μmol/L)

10.2§

3.7

9.5§

7.9, 11.6

--

--

Insulin (mU/L)

15.7‡

24.0

12.0‡

8.0, 18.5

--

--

HbA1c (%)

7.1†

1.4

6.9†

6.1, 7.8

--

--

  1. * Average of Visit 2 and Visit 3.
  2. † Average of Visit 1 and Visit 3.
  3. ‡ Visit 1 only.
  4. § Visit 3 only.
  5. ¶ Baseline HDLc (mean ± SD): men = 1.03 ± 0.23 mmol/L, women = 1.21 ± 0.28 mmol/L
  6. || All changes at six weeks were statistically significant at P < 0.0001
  7. -- not measured