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Table 1 Baseline characteristics of the FIELD study cohort

From: Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]

Characteristic Category Screened, not randomized (n= 4105) Randomized (n= 9795)
n %         n %
Sex Male 2424 59.0 6138 62.7
  Female 1681 41.0 3657 37.3
Age at Visit 1 (years) <55 682 16.6 1668 17.0
  55–59 802 19.5 1976 20.2
  60–64 856 20.8 2196 22.4
  65–69 888 21.7 2202 22.5
  70+ 877 21.4 1753 17.9
Ethnicity* Caucasian 3757 91.5 9093 92.8
  Indigenous 161 3.9 258 2.6
  Asian 93 2.3 141 1.4
  Other 94 2.3 303 3.1
Body mass index (kg/m2) (BMI) BMI < 25 805 19.6 1198 12.2
  25 ≤ BMI < 30 1511 36.8 3855 39.4
  30 ≤ BMI < 35 1099 26.8 2869 29.3
  BMI ≥ 35 652 15.9 1866 19.1
Waist (cm) Female (mean ± SD) 98 ± 15   101 ± 14  
  Male (mean ± SD) 103 ± 13   105 ± 12  
Waist-hip ratio ratio < 0.8 242 5.9 333 3.4
  0.8 ≤ ratio < 0.9 1184 28.8 2531 25.8
  0.9 ≤ ratio < 1.0 1931 47.0 4942 50.5
  1.0 ≤ ratio < 1.1 645 15.7 1797 18.4
  ratio ≥ 1.1 73 1.8 179 1.8
Smoking (cigarettes) Nonsmoker 1735 42.3 4000 40.8
  Ex-smoker 1933 47.1 4908 50.1
  Current smoker 404 9.8 887 9.1
Clinical history Prior cardiovascular disease † 1045 25.4 2131 21.8
  Prior myocardial infarction 278 6.7 485 5.0
  Stroke 194 4.7 346 3.5
  Angina 588 14.3 1188 12.1
  Hypertension 2247 54.7 5544 56.6
  Claudication or peripheral vascular disease 351 8.6 711 7.2
  Transient ischemic attack 155 3.8 307 3.1
Prior coronary revascularisation No CABG or PTCA 3908 95.2 9432 96.3
  CABG only 122 3.0 230 2.4
  PTCA only 49 1.2 102 1.0
  CABG and PTCA 26 0.6 31 0.3
Diabetes management Diet only 1119 27.3 2542 26.0
  Diet + OH only 2238 54.5 5874 60.0
  Diet + insulin 429 10.5 569 5.8
  Diet + OH + insulin 319 7.8 810 8.3
Diabetic complications ‡ Retinopathy 431 10.5 814 8.3
  Neuropathy 636 15.5 1394 14.2
  Nephropathy 161 3.9 279 2.9
  Skin ulcers 139 3.4 299 3.1
  Amputations 106 2.6 176 1.8
Diabetes diagnosis ‡ Age at diagnosis (mean ± SD) 54.8 ± 8.7   55.5 ± 8.3  
  Median duration of diabetes in years (quartile 1, quartile 3) 6 (2, 11)   5 2, 10  
  1. * Patients are assumed to be Caucasian unless otherwise stated. Indigenous includes Aborigines, Torres Strait Islanders, Maori and Pacific Islanders. Other includes mixed races, African-American, Indian, African, etc.
  2. † Prior cardiovascular disease is defined as a reported history of myocardial infarction, angina (stable and unstable), coronary revascularization (CABG or PTCA), stroke, claudication or peripheral vascular disease or peripheral revascularization before randomization. The count includes 13 randomized patients and 10 nonrandomized patients who suffered or reported a cardiovascular event during the run-in period (visit 1 to visit 4 (randomization)).
  3. ‡ Diabetic complications and age at diabetes diagnosis are self-reported.
  4. CABG = coronary artery bypass grafting; PTCA = percutaneous transluminal coronary angioplasty; SD = standard deviation; OH = oral hypoglycemic agents