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Table 3 Secondary causes of low HDL-C

From: Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review

1.

Elevated triglycerides.

(Component of metS)

 

End stage renal disease

 

Hypothyroidism [also increased total Chol/HDL-C ratio.

2.

Obesity and Overweight. – [waist measurement] –

(Component of metS)

 

[Visceral obesity in particular]

 

For every 3 kg. (7 lbs.) weight loss HDL-C increased 1 mg/dL.

3.

Prediabetes and overt Type 2 Diabetes Mellitus.

(Component of metS)

4.

Physical inactivity

(lifestyle choice).

5.

Smoking

(lifestyle choice).

6.

Very high carbohydrate intakes > 50–60% of energy

(lifestyle choice).

 

[Especially Fructose Containing Soft Drinks.]

7.

Metabolic Syndrome: As potent a risk factor as smoking.

8.

Drugs, such as beta-blockers, anabolic steroids, and progestational agents.