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Table 1 Comparisons of the human NOS enzymes

From: Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycemia a late manifestation? The role of NOS, NO, and redox stress.

nNOS NOS-1

Chromosome 12

Amino acids 1434 aa 161 kDa

high Ca++ requirement

iNOS NOS-2

Chromosome 17

Amino acids 1153 aa 131 kDa

low Ca++ requirement

eNOS NOS-3

Chromosome 7

Amino acids 1203 aa 133 kDa

high Ca++ requirement

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Cardiovascular Diabetology

ISSN: 1475-2840