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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Vascular endothelial growth factor (VEGF) fails to improve blood flow and to promote collateralization in a diabetic mouse ischemic hindlimb model

Figure 3

Ratio of smooth muscle actin positive cells in the ischemic to nonischemic limb in the proximal and distal limb segments. Each group contains 4 or 5 animals. Ratio and P Values: Proximal: VEGF arm (1.8) Vs. Placebo (1.5) p < 0.05, Vs both DM arms p < 0.001, Normal placebo Vs. both DM arms p < 0.001, DM VEGF (4.5) Vs DM-Placebo (3.6) p < 0.05. Distal: VEGF arm (1.0) Vs. Placebo (1.1) p = NS, Vs DM-VEGF p < 0.001, Vs. DM-Placebo p < 0.01, DM VEGF (14.6) Vs DM-Placebo (1.7) p < 0.01.

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