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Table 1 Lipoprotein and fibrinogen concentrations during atorvastatin and fenofibrate therapy (n = 11).

From: Differential effects of fenofibrate versus atorvastatin on the concentrations of E-selectin and vascular cellular adhesion molecule-1 in patients with type 2 diabetes mellitus and mixed hyperlipoproteinemia: a randomized cross-over trial

  atorvastatin fenofibrate
before (mg/dL) during (mg/dL) change (%) before (mg/dL) during (mg/dL) change (%)
Total cholesterol 260 ± 46 193 ± 45 -25*** 270 ± 48 219 ± 26 -17***
Total triglycerides 313 ± 198 210 ± 63 -11 320 ± 190 162 ± 48 -42***
LDL-cholesterol 150 ± 39 108 ± 39 -28** 161 ± 48 142 ± 23 -7
   large, buoyant 15.2 ± 7.1 10.8 ± 5.4 -27** 17.8 ± 9.4 14.2 ± 3.6 -10
   intermediate dense 57.8 ± 25.2 42.8 ± 19.4 -22* 61.8 ± 29.0 75.9 ± 20.2 +31
   small, dense 85.9 ± 13.4 57.8 ± 17.5 -23* 91.8 ± 17.8 61.9 ± 19.2 -32*
HDL-cholesterol 46.8 ± 9.4 51.1 ± 10.4 +15* 50.6 ± 12.6 55.1 ± 11.6 +14*
Fibrinogen 406 ± 41 400 ± 41 -1 411 ± 57 329 ± 32 -19**
  1. a: *p < 0.05; **p < 0.01; ***p < 0.005. b: LDL subtypes refer to following density intervals: large buoyant LDL 1.020 – 1.029 g/mL, intermediate dense LDL 1.030 – 1.034 g/mL, small dense LDL 1.041–1.066 g/mL. c: The data from 10 out of 11 patients were published previously [16].