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Table 3 Blood pressure (mmHg) of subjects not treated with an antihypertensive drug, according to α2B-AR I/D genotypes

From: The insertion/deletion variation in the α2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes

  AMI No AMI
  DD (n = 3) ID (n = 12) II (n = 8) P* ID + II (n = 20) P* DD (n = 14) ID (n = 26) II (n = 32) P* ID + II (n = 58) P*
Systolic BP 144 ± 9 144 ± 3 130 ± 6 0.090 139 ± 3 0.54 154 ± 8 136 ± 4 146 ± 4 0.043 141 ± 3 0.055
Diastolic BP 86 ± 5 83 ± 3 77 ± 3 0.28 81 ± 2 0.43 86 ± 4 77 ± 2 82 ± 2 0.067 80 ± 1 0.065
  1. *One-way ANOVA was used in the comparison of BP between the three genotype groups; t test was used in the comparison of BP of carriers of the DD genotype with carriers of the other genotypes combined. I, insertion; D, deletion