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Table 3 Blood pressure (mmHg) of subjects not treated with an antihypertensive drug, according to α2B-AR I/D genotypes

From: The insertion/deletion variation in the α2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes

 

AMI

No AMI

 

DD (n = 3)

ID (n = 12)

II (n = 8)

P*

ID + II (n = 20)

P*

DD (n = 14)

ID (n = 26)

II (n = 32)

P*

ID + II (n = 58)

P*

Systolic BP

144 ± 9

144 ± 3

130 ± 6

0.090

139 ± 3

0.54

154 ± 8

136 ± 4

146 ± 4

0.043

141 ± 3

0.055

Diastolic BP

86 ± 5

83 ± 3

77 ± 3

0.28

81 ± 2

0.43

86 ± 4

77 ± 2

82 ± 2

0.067

80 ± 1

0.065

  1. *One-way ANOVA was used in the comparison of BP between the three genotype groups; t test was used in the comparison of BP of carriers of the DD genotype with carriers of the other genotypes combined. I, insertion; D, deletion