Table 2 Odds ratios for hypertension in relation to the α_2B-adrenoceptor genotype and other cardiovascular risk factors.

Univariate models

   α_2B-AR D vs. I

1.6 (0.6–4.7)

0.36

1.8 (0.9–3.7)

0.12

   α_2B-AR ID vs. II

1.4 (0.4–4.1)

0.59

1.3 (0.6–2.8)

0.53

   α_2B-AR DD vs. II

2.6 (0.5–13.2)

0.26

3.7 (1.2–11.1)

0.021

   α_2B-AR DD vs. II + ID

2.2 (0.5–10)

0.36

3.2 (1.2–8.9)

0.026

   Age

1.0 (0.9–1.0)

0.79

1.1 (1.0–1.1)

0.008

   BMI

1.1 (1.0–1.4)

0.037

1.1 (1.0–1.2)

0.038

   LDL cholesterol

1.3 (1.0–1.8)

0.059

1.5 (1.0–2.2)

0.032

   Smoking

0.6 (0.2–2.0)

0.43

0.5 (0.2–1.2)

0.11

   Diabetes

1.9 (0.6–5.8)

0.29

1.3 (0.6–2.7)

0.48

Multivariate model*

   α_2B-AR DD vs. II + ID

N/A

4.0 (1.2–13.3)

0.024

   Age

N/A

1.1 (1.0–1.1)

0.020

   BMI

N/A

1.2 (1.0–1.4)

0.006

   LDL cholesterol

N/A

1.8 (1.1–3.0)

0.032