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Table 3 Association of mortality with genotype, HbA 1c and platelet morphology in non-diabetic participants

From: PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort

 

HbA1c≤5.5%

 

5.5% < HbA1c< 6.5%

(HbA1c≤37 mmol/mol)

(37 mmol/mol < HbA1c< 48 mmol/mol)

(N = 2,192)

(N = 1,627)

HR (95% CI)

P

HR (95% CI)

P

Genotype AxA2

0.87 (0.54, 1.41)

0.57

0.99 (0.66, 1.53)

0.97

HbA1c

0.67 (0.24, 1.83)

0.43

2.47 (1.04, 5.88)

0.04

Platelet count

1.03 (1.00, 1.07)

0.03

0.99 (0.96, 1.02)

0.67

Platelet mass

1.00 (0.99, 1.00)

0.03

1.00 (0.995, 1.003)

0.95

MPV

2.13 (0.98, 4.60)

0.06

1.03 (0.51, 2.08)

0.93

  1. The hazard ratios (HR) with 95% confidence interval (CI) for every unit increase of the variables are shown. Multivariate analysis of the association between mortality and genotype, HbA1c and platelet markers, were taken with adjustment of age, sex, waist-hip ratio, blood pressure (diastolic and systolic), cholesterol (total, HDL, LDL), smoking status (categorized: non-smoker, former smoker, current smoker), alcohol intake (categorized: ≥20 g/day for women; ≥40 g/day for men), physical activity (categorized: >1 h per week).
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Cardiovascular Diabetology

ISSN: 1475-2840