PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort

Table 1 Population characteristics

	Surviving persons	Deceased persons	P
N [subjects]	3,789	239
No. of diabetic subjects	156 (4.1%)	53 (22.2%)	<0.0001
GenotypeAxA2 [%]	27.6%	30.1%	>0.05
Age [years]	48.2 ± 13.7	63.3 ± 9.7	<0.0001
	range : 54–75 years	range : 35–75 years
BMI [kg/m²]	27.1 ± 4.6	28.6 ± 4.7	<0.0001
Waist to hip-ratio	0.864 ± 0.088	0.932 ± 0.083	<0.0001
Blood pressure diastolic [mm Hg]	80.3 ± 10.4	80.9 ± 11.3	>0.05
Blood pressure systolic [mm Hg]	127.7 ± 19.0	139.6 ± 22.1	<0.0001
HbA_1c [%]	5.55 ± 0.58	5.90 ± 0.95	<0.0001
HbA_1c [mmol/mol]	37.2 ± 6.3	41.0 ± 10.4
FBG [mg/dl]	106.6 ± 33.1	118.0 ± 42.9	<0.0001
	(1,428 subjects)	(201 subjects)
Total cholesterol [mg/dl]	226.7 ± 43.3	235.6 ± 49.5	0.0014
HDL cholesterol [mg/dl]	57.8 ± 17.0	55.9 ± 16.8	>0.05
LDL cholesterol [mg/dl]	136.6 ± 41.4	145.7 ± 42.9	0.0012
Mean platelet volume [fl]	8.722 ± 0.94	8.834 ± 1.066	0.061
Platelet count [/nl]	244.4 ± 57.3	220.9 ± 65.4	0.0001
Platelet mass	2,108 ± 450	1,924 ± 519	0.0001

Analysis results of the population characteristics are reported as mean ± standard deviation (SD). Comparison between the groups are calculated by Mann–Whitney testing or one-way ANOVA followed by Dunnett’s multiple comparison post-test for continuous data and Fisher’s exact test for categorical data.

ISSN: 1475-2840