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Table 2 Hemodynamic variables in control and diabetic TGR(mRen-2)27 rats, treated with vehicle or curcumin

From: High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

 

Control

Diabetes

Diabetes + Curcumin

Heart rate (bpm)

348 ± 22

237 ± 14a

226 ± 10a

ESP (mmHg)

138 ± 15

116 ± 7

114 ± 5.6

EDP (mmHg)

8 ± 1

10 ± 0.5

10 ± 1.1

Tau-Weiss (msec)

18.9 ± 2.4

25.5 ± 0.9a

18.5 ± 1.2b

ESPVR (mmHg/mL)

0.54 ± 0.23

0.32 ± 0.07a

0.46 ± 0.05

EDPVR (mmHg/mL)

0.029 ± 0.004

0.049 ± 0.003a

0.026 ± 0.002b

  1. ESP is end systolic pressure; EDP is end diastolic pressure; ESPVR is the end systolic pressure volume relationship; EDPVR is the end diastolic pressure volume relationship.
  2. ap < 0.05 compared with control, bp < 0.05 compared with diabetes group.