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Figure 2 | Cardiovascular Diabetology

Figure 2

From: High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

Figure 2

3H-proline incorporation as a marker of collagen synthesis: HG and TGF-β increased collagen production, in a synergistic manner in cardiac fibroblasts. Curcumin at 25 μM reduced collagen synthesis in both HG and TGF-β stimulated H9c2 cells. (*†p < 0.01 c/w NG, ‡p < 0.01 c/w HG/TGF, ∞p < 0.01 c/w HG, ≠p < 0.01 c/w NG + TGF, #p < 0.01 c/w HG + TGF)

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