Figure 6
From: Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes
Role of calpain in endothelium-dependent and -independent relaxation. Aortic rings were pre-contracted by phenylephrine and the subsequent responses to acetylcholine (Ach) or sodium nitroprusside (SNP) were recorded. (A-C) the response to Ach in STZ-induced mice (A), OVE26 mice (B), and eNOS knockout mice (C) (D-F). the response to SNP in STZ-induced mice (D), OVE26 mice (E), and eNOS knockout mice (F). Data are given as mean ± SD, n = 6-8. *P < 0.05.