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Table 1 Clinical and laboratory data in patients with type 1 diabetes and control subjects

From: Influence of a family history of type 2 diabetes, demographic and clinical data on carotid intima-media thickness in patients with type 1 diabetes: a cross-sectional study

 

Type 1 diabetes

Control

P

Demographic data

N (% male)

127 (45.7)

125 (40.8)

0.4

Age (years)

32 (23–42)

29 (22–39.5)

0.08

Age at diagnosis (years)

15 (10–22)

  

Duration of diabetes (years)

14 (10–21.8)

  

Past history of hypertension (%)

24.8%

  

Current smoke (%)

9.6

10.4

0.8

Current alcohol consumption (%)

30.4

58.3

<0.001

Current exercise practice (%)

42,4

50.6

0.3

Family history

Family history of type 2 diabetes (%)

29,8

25.2

0.5

Family history of type 1 diabetes (%)

19.2

18.3

0.9

Family history of hypertension (%)

64

52.2

0.07

Family history of CVD (%)

21

13

0.1

Anthropometric data and insulin dose

BMI (kg/m2)

23.6 (21.6-26.2)

24.3 (21.6-28)

0.2

SBP (mmHg)

120 (110–125.8)

113 (105–120)

0.06

DBP (mmHg)

70 (70–80)

70 (68.5-80)

0.2

Waist (cm)

81 (74–88)

81 (73.1-89.9)

0.9

WHR

0.86 (0.8-0.9)

0.85 (0.79-0.91)

0.5

Insulin/weight (U/Kg)

0.81 (0.59-1.07)

  

Laboratory data

Fasting glucose (mg/dL)

117 (78–260)

78 (70.5-85.5)

<0.001

HbA1c (%)

8.9 (7.8-10.5)

5.4 (5.2-5.8)

<0.001

Creatinine (mg/dL)

0.86 (0.7-1.0)

0.93 (0.77-1.09)

0.007

Creatinine clearance (mL/min)

112.7 (88.5-131.3)

103.5 (87.4-119.4)

0.1

Uric acid (mg/dL)

3.7 (2.9-4.5)

5.1 (4.0-6.3)

<0.001

Total cholesterol (mg/dL)

163 (148–189)

167.5 (146–197.8)

0.3

Triglycerides (mg/dL)

74.5 (57–108.8)

91 (68–129.5)

0.05

HDL (mg/dL)

55.7 (44.7-67.4)

54.9 (44.1-65.8)

0.3

LDL (mg/dL)

90.1 (74.9-105.3)

96 (73.3-115.5)

0.07

CRP (mg/dL)

0.144 (0.066-0.340)

0.120 (0.030-0.320)

0.2

UAER (mcg/min)

8.56 (4.31-25.33)

3.39 (2.11-5.99)

<0.001

IMT data

IMT on the right (mm)

0.533 (0.497-0.600)

0.513 (0.478-0.555)

0.002

IMT on the left (mm)

0.530 (0.490-0.610)

0.510 (0.475-0.562)

0.005

Total IMT (mm)

0.538 (0.500-0.607)

0.513 (0.481-0.557)

0.001

  1. N = Number, CVD = Cardiovascular disease, BMI = Body mass index, SBP = Systolic blood pressure, DBP = Diastolic blood pressure, WHR = Waist to hip ratio, U = International units, HbA1c = Glycated hemoglobin, HDL = High density lipoprotein, LDL = Low density lipoprotein, CRP = C reactive protein, UAER = Urinary Albumin excretion rate, IMT = intima media thickness. Data are presented in median and interquartile range (IQR).
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Cardiovascular Diabetology

ISSN: 1475-2840