From: Vascular calcification in patients with type 2 diabetes: the involvement of matrix Gla protein
 | All | [dp-ucMGP] ≤ 559.5 pM | [dp-ucMGP] > 559.5 pM | p |
---|---|---|---|---|
 | n = 198 | n = 99 | n = 99 |  |
Age (years) | 64 ± 8 | 63 ± 9 | 66 ± 8 | 0.002 |
Diabetes duration (years) | 15 ± 10 | 14 ± 10 | 15 ± 9 | 0.358 |
Male gender n (%) | 158 (80) | 82 (83) | 76 (77) | 0.288 |
Body mass index (kg/m 2 ) | 29 ± 5 | 28 ± 5 | 30 ± 5 | <0.0001 |
SBP (mmHg) | 127 ± 17 | 126 ± 17 | 128 ± 17 | 0.377 |
DBP (mmHg) | 73 ± 9 | 73 ± 9 | 72 ± 8 | 0.487 |
Smoking habit n (%) | 119 (60) | 58 (59) | 61 (62) | 0.663 |
Previous CVD n (%) | 139 (70) | 66 (67) | 73 (74) | 0.277 |
Glycaemia (mmol/l) | 8.2 ± 2.8 | 8.0 ± 2.6 | 8.3 ± 2.9 | 0.401 |
(7.8) | (7.6) | (8.0) | Â | |
HbA1c (%) | 7.8 ± 1.5 (7.5) | 7.7 ± 1.4 | 7.9 ± 1.5 | 0.572 |
 | (7.5) | (7.5) |  | |
GFR MDRD (mmol/l) | 80 ± 19 | 82 ± 19 | 70 ± 19 | <0.0001 |
Microalbuminuria (mg/l) | 166 ± 840 | 169 ± 1132 | 162 ± 373 | <0.0001 |
(23) | (14) | (33) | Â | |
Calcium (mmol/l) | 2.30 ± 0.10 | 2.30 ± 0.10 | 2.34 ± 0.10 | 0.055 |
Phosphate (mmol/l) | 1.02 ± 0.15 | 1.04 ± 0.20 | 1.00 ± 0.20 | 0.164 |
Intact PTH | 54.5 ± 27.5 | 50.8 ± 26.0 | 58.5 ± 28.9 | 0.030 |
(pg/mL) | (46.9) | (45.2) | (52.0) | Â |
25(OH)Vit D (ng/ml) | 13.8 ± 8.4 | 14.4 ± 8.2 | 13.2 ± 8.5 | 0.175 |
(12.0) | (13.0) | (11.0) | Â | |
CRP | 2.2 ± 1.5 | 2.2 ± 2.6 | 2.2 ± 2.5 | 0.725 |
(mg/l) | (1.2) | (1.3) | (1.1) | Â |
Triglycerides | 1.6 ± 1.1 | 1.4 ± 1.1 | 1.6 ± 0.9 | 0.039 |
(mmol/L) | (1.3) | (1.2) | (1.4) | Â |
Total cholesterol (mmol/l) | 3.7 ± 0.9 | 3.7 ± 0.8 | 3.8 ± 0.9 | 0.283 |
LDL cholesterol | 1.9 ± 0.7 | 1.9 ± 0.7 | 2.0 ± 0.8 | 0.403 |
(mmol/L) | (1.8) | (1.8) | (1.8) | Â |
Total cholesterol/HDL | 3.7 ± 1.6 | 3.5 ± 1.1 | 3.9 ± 1.8 | 0.053 |
cholesterol | (3.5) | (3.3) | (3.5) | Â |
Peripheral calcification score | 2528 ± 5779 | 1609 ± 3983 | 3447 ± 7040 | <0.0001 |
(524) | (274) | (1096) | Â | |
t-ucMGP (nM) | 4868 ± 1613 | 4815 ± 1689 | 4921 ± 1539 (4787) | 0.460 |
(4741) | (4616) | Â | Â | |
dp-ucMGP (pM) | 627 ± 451 | 342 ± 142 | 912 ± 474 | NA |
 | (559) | (352) | (755) |  |
VKA treatment n (%) | 6 (3) | 0 (0) | 6 (6) | 0.013 |