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Table 1 Mean V max ,K m and R2for the rate of glucose consumption in bovine aortic endothelial cells

From: Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle

  Basal GKA (RO28-1675) (10 μM) TGF-β (2 ng/ml)
Vmax 0.14 ± 0.02 0.17 ± 0.02 0.21 ± 0.01
Km 6.42 ± 1.97 9.08 ± 2.12 4.47 ± 0.83
R2 0.83 0.92 0.91
  1. Results are mean ± SEM of three separate experiments.