Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment

Table 1 Summary of miRNA in HUVEC exposed to a diabetic environment with and without calcitrol

miRNA ID	Diabetic environment^a		Diabetic environment and calcitrol
	Fold change	p-value	Fold change	p-value
hsa-mir-600	1.53	0.014	-1.35	0.036
hsa-mir-10b	1.49	0.01	-1.31	0.032
hsa-mir-640	1.31	0.006	-1.35	0.004
hsa-miR-510	1.35	0.018	-1.49	0.03
hsa-miR-659	1.37	0.13	1.99	0.0005
hsa-mir-320e	1.88	0.002	-1.12	0.19
miR-425-star	1.8	0.01	-1.48	0.034
hsa-miR-181c	-1.15	0.14	3.26	0.01
hsa-miR-411	-1.57	0.015	2.33	0.002
hsa-miR-133b	-1.73	0.002	1.19	0.056
hsa-miR-613	-1.91	0.005	1.38	0.036
hsa-miR-335	-1.71	0.037	1.97	0.019
hsa-miR-642	-1.48	0.006	1.23	0.036
hsa-miR-670	-1.41	0.026	1.53	0.014
hsa-miR-20b	-2.62	0.072	2.86	0.09
hsa-miR-15a	-4.54	0.07	3.69	0.11
hsa-miR-126	-1.76	0.07	1.55	0.14

^a200 μg/ml AGE-HSA and 250 mg/dl glucose vs. control (200 μg/μl HSA and 100 mg/dl glucose).

ISSN: 1475-2840