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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment

Figure 3

Predicted miRNA-target protein biological interactions, including direct and indirect associations. The predicted gene targets were found to correspond to biological processes such as immune and defense responses, signal transduction and regulation of RNA and primary metabolic processes. The genes that were further analyzed and discussed, KLF6, KLF9, KLF10, TXNIP and IL8 are marked with a ring. These gene targets were chosen because they take part in cellular growth, differentiation, proliferation, apoptosis and angiogenesis, as well as in regulating endothelial cell metabolism, growth, and inflammation.

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Cardiovascular Diabetology

ISSN: 1475-2840