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Figure 8 | Cardiovascular Diabetology

Figure 8

From: Streptozotocin-induced diabetes prolongs twitch duration without affecting the energetics of isolated ventricular trabeculae

Figure 8

Twitch stress, length change and rate of heat production of isotonic work-loops. (A) Steady-state twitch stress of an isometric contraction (a) superimposed with work-loop twitch stress profiles at various afterloads (b – h) of a representative trabecula. (B) Corresponding length changes throughout the time-courses of twitch stresses in A. The grey circles indicate the locations at which velocities of muscle shortening were maximal. (C) Parametric plots of the data in A against those in B. (D) Record of rate of heat production for 7 variously-afterloaded work-loop contractions (b – h), bracketed by 8 isometric contractions (a).

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