Cardiovascular Diabetology

Table 3 Association results for the genotyped exonic variants with clinical and subclinical CVD and blood lipids

From: Analysis of common and coding variants with cardiovascular disease in the diabetes heart study

		Additive			Dominant			Recessive
SNP	Trait	P-value	β value	SE	P-value	β value	SE	P-value	β value	SE
rs3135506	Triglycerides	5×10 ⁻⁵	0.189	0.465	3×10⁻⁴	0.17	0.31	7×10⁻⁴	0.93	0.27
rs3135506	LDL	0.0012	−9.48	2.92	7×10⁻⁴	−10.1	2.99	0.65	10.1	22.4
rs3135506	HDL	0.0066	−0.20	0.07	0.011	−0.19	0.07	0.13	−0.63	0.42
rs651821	Triglycerides	8×10⁻⁴	0.15	0.04	0.004	0.14	0.05	0.005	0.5	0.18
rs651821	History of CVD	0.02	0.27	0.11	0.08	0.23	0.13	0.009	1.29	0.56
rs138326449	Triglycerides	0.0017	−0.97	0.31	0.0017	−0.97	0.31	NA	NA	NA
rs138326449	HDL	0.13	1.16	0.46	0.013	1.16	0.46	NA	NA	NA
rs45456595	IMT	0.0022	0.07	0.02	0.0022	0.07	0.02	NA	NA	NA
rs5128	Triglycerides	0.0096	0.10	0.04	0.03	0.09	0.04	0.01	0.41	0.16
rs72650673	Triglycerides	0.0084	0.77	0.29	0.0084	0.77	0.29	NA	NA	NA

Associations were examined under additive, dominant and recessive genetic models. Bold indicates statistical significance. History of CVD = prior reports of CVD events, IMT = carotid intima-media thickness, SE = standard error.

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ISSN: 1475-2840

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