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Table 3 Association results for the genotyped exonic variants with clinical and subclinical CVD and blood lipids

From: Analysis of common and coding variants with cardiovascular disease in the diabetes heart study

   Additive Dominant Recessive
SNP Trait P-value β value SE P-value β value SE P-value β value SE
rs3135506 Triglycerides 5×10 −5 0.189 0.465 3×10−4 0.17 0.31 7×10−4 0.93 0.27
rs3135506 LDL 0.0012 −9.48 2.92 7×10−4 −10.1 2.99 0.65 10.1 22.4
rs3135506 HDL 0.0066 −0.20 0.07 0.011 −0.19 0.07 0.13 −0.63 0.42
rs651821 Triglycerides 8×10−4 0.15 0.04 0.004 0.14 0.05 0.005 0.5 0.18
rs651821 History of CVD 0.02 0.27 0.11 0.08 0.23 0.13 0.009 1.29 0.56
rs138326449 Triglycerides 0.0017 −0.97 0.31 0.0017 −0.97 0.31 NA NA NA
rs138326449 HDL 0.13 1.16 0.46 0.013 1.16 0.46 NA NA NA
rs45456595 IMT 0.0022 0.07 0.02 0.0022 0.07 0.02 NA NA NA
rs5128 Triglycerides 0.0096 0.10 0.04 0.03 0.09 0.04 0.01 0.41 0.16
rs72650673 Triglycerides 0.0084 0.77 0.29 0.0084 0.77 0.29 NA NA NA
  1. Associations were examined under additive, dominant and recessive genetic models. Bold indicates statistical significance. History of CVD = prior reports of CVD events, IMT = carotid intima-media thickness, SE = standard error.