Cardiovascular Diabetology

Table 2 Nominally significant results for the GWAS and imputation SNPs with measures of CVD and lipids

From: Analysis of common and coding variants with cardiovascular disease in the diabetes heart study

			Additive			Dominant			Recessive
SNP	Gene	Trait	P-value	β value	SE	P-value	β value	SE	P-value	β value	SE
rs1746048	CXCL12	All-cause mortality	0.005	0.29	0.12	0.005	0.32	0.12	0.28	0.43	0.44
rs599839	PSRC1	CAC	0.008	−0.31	0.12	0.009	−0.36	0.14	0.27	−0.36	0.32
rs646776	CELSR2, PSRC1, SORT1	CAC	0.013	−0.31	0.12	0.010	−0.38	0.15	0.41	−0.28	0.34
rs17398575	PIK3CG	AACP	0.015	8.74	3.58	0.009	11.03	4.20	0.60	4.85	9.33
rs3809346	COL4A1, COL4A2	CVD-cause mortality	0.026	−0.18	0.08	0.36	−0.11	0.12	0.004	−0.39	0.14
rs4773144	COL4A1, COL4A2	CVD-cause mortality	0.040	−0.16	0.08	0.43	−0.095	0.12	0.007	−0.38	0.14

Associations were examined under additive, dominant and recessive genetic models. CAC = coronary artery calcified plaque; AACP = infrarenal abdominal aortic calcified plaque SE = standard error.

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ISSN: 1475-2840

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