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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

Figure 4

Pim-1 downregulated in human diabetic heart. A-B representative blots and bar graphs showing the levels of Pim-1 (A) and pAkt/Akt (B) in right atrial appendage samples collected from diabetic and non-diabetic patients undergoing on-pump coronary artery bypass graft surgery. C-D. Bar graphs showing the expression level of miR-1 (C) and miR-208a (D) in diabetic and non-diabetic human heart. n = at least 7 in each group. ND – non-diabetic; D – Diabetic. Values are means ± SD. **P < 0.01 and ***P < 0.001 vs. non-diabetic of corresponding gender. #P < 0.05 vs. male diabetic.

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