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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

Figure 1

Rapid onset of cardiomyopathy in STZ-induced female diabetic mice. Line graphs showing the mitral valve flow velocity (A) and indexes of left ventricle (LV) function assessed (B, C & D) by the serial echocardiogram at different time points from STZ or STZ-vehicle (n = at least 8 at each time point). LVEF – LV ejection fraction, ESV – LV end systolic volume, LVAWs – LV anterior wall thickness during systole. Values are means ± SD. Results of pair-wise comparison are illustrated. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. non-diabetic of corresponding gender at corresponding time point. #P < 0.05 and ##P < 0.01 vs. male diabetic at corresponding time point.

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