|
Male
|
Female
|
---|
|
C57B6/J#(n = 8)
|
db/db#(n = 8)
|
C57B6/J (n = 6)
|
db/db(n = 5)
|
---|
Body weight (g)
|
36.50 ± 1.46
|
62.50 ± 3.33**
|
35.00 ± 0.84
|
57.80 ± 4.84**
|
Glucose (mg/dL)
|
206.88 ± 10.74
|
398.00 ± 19.89**
|
219.17 ± 9.04
|
307.20 ± 41.11*
|
TC (mg/dL)
|
74.63 ± 4.69
|
188.88 ± 16.00**
|
73.17 ± 2.23
|
183.60 ± 10.80**
|
TG (mg/dL)
|
47.13 ± 5.78
|
52.88 ± 6.24
|
41.33 ± 8.10
|
49.40 ± 7.05
|
HDL-C (mg/dL)
|
51.00 ± 3.29
|
97.25 ± 8.24**
|
50.83 ± 2.82
|
89.60 ± 7.92**
|
LDL-C (mg/dL)
|
14.20 ± 1.89
|
81.05 ± 11.29**
|
14.07 ± 4.08
|
84.12 ± 6.04**
|
- Values represent the mean ± standard error of the mean. TC total cholesterol; TG triglyceride; HDL-C HDL cholesterol; LDL-C LDL cholesterol. Variation between groups was determined by using the two-independent-sample test with the Mann–Whitney U test for comparisons. *P < 0.05, **P < 0.01 vs gender-matched control group. #No parameter was significantly different from that of female mice of the same genotype.