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Table 2 Gender-stratified characteristics of leptin receptor–deficient ( db/db ) mice and wild-type (C57B6/J) littermates

From: Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL

  Male Female
  C57B6/J#(n = 8) db/db#(n = 8) C57B6/J (n = 6) db/db(n = 5)
Body weight (g) 36.50 ± 1.46 62.50 ± 3.33** 35.00 ± 0.84 57.80 ± 4.84**
Glucose (mg/dL) 206.88 ± 10.74 398.00 ± 19.89** 219.17 ± 9.04 307.20 ± 41.11*
TC (mg/dL) 74.63 ± 4.69 188.88 ± 16.00** 73.17 ± 2.23 183.60 ± 10.80**
TG (mg/dL) 47.13 ± 5.78 52.88 ± 6.24 41.33 ± 8.10 49.40 ± 7.05
HDL-C (mg/dL) 51.00 ± 3.29 97.25 ± 8.24** 50.83 ± 2.82 89.60 ± 7.92**
LDL-C (mg/dL) 14.20 ± 1.89 81.05 ± 11.29** 14.07 ± 4.08 84.12 ± 6.04**
  1. Values represent the mean ± standard error of the mean. TC total cholesterol; TG triglyceride; HDL-C HDL cholesterol; LDL-C LDL cholesterol. Variation between groups was determined by using the two-independent-sample test with the Mann–Whitney U test for comparisons. *P < 0.05, **P < 0.01 vs gender-matched control group. #No parameter was significantly different from that of female mice of the same genotype.