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Table 2 Gender-stratified characteristics of leptin receptor–deficient ( db/db ) mice and wild-type (C57B6/J) littermates

From: Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL

 

Male

Female

 

C57B6/J#(n = 8)

db/db#(n = 8)

C57B6/J (n = 6)

db/db(n = 5)

Body weight (g)

36.50 ± 1.46

62.50 ± 3.33**

35.00 ± 0.84

57.80 ± 4.84**

Glucose (mg/dL)

206.88 ± 10.74

398.00 ± 19.89**

219.17 ± 9.04

307.20 ± 41.11*

TC (mg/dL)

74.63 ± 4.69

188.88 ± 16.00**

73.17 ± 2.23

183.60 ± 10.80**

TG (mg/dL)

47.13 ± 5.78

52.88 ± 6.24

41.33 ± 8.10

49.40 ± 7.05

HDL-C (mg/dL)

51.00 ± 3.29

97.25 ± 8.24**

50.83 ± 2.82

89.60 ± 7.92**

LDL-C (mg/dL)

14.20 ± 1.89

81.05 ± 11.29**

14.07 ± 4.08

84.12 ± 6.04**

  1. Values represent the mean ± standard error of the mean. TC total cholesterol; TG triglyceride; HDL-C HDL cholesterol; LDL-C LDL cholesterol. Variation between groups was determined by using the two-independent-sample test with the Mann–Whitney U test for comparisons. *P < 0.05, **P < 0.01 vs gender-matched control group. #No parameter was significantly different from that of female mice of the same genotype.
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Cardiovascular Diabetology

ISSN: 1475-2840