Figure 2

Comparison of LDL electronegativity and protein composition between db/db and wild-type mice. A, Representative results of agarose gel electrophoresis showing the relative electronegativity of LDL isolated from male and female db/db (KO) and wild-type (WT) mice. Relative mobility (Rf) was compared among groups. B, Representative results of SDS-PAGE showing the relative concentration of ApoCIII in LDL isolated from male and female db/db (KO) and wild-type (WT) mice. C, Western blot analysis of ApoCIII and ApoB100 protein levels in LDL isolated from male and female db/db (KO) and wild-type (WT) mice. The ratio of ApoCIII to ApoB100 was compared among groups. n = 5 for each group.