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Table 3 Association of elevated high-sensitivity troponin I (hs-TnI) with subsequent major adverse cardiovascular events (MACE), heart failure, myocardial infarction and cardiovascular mortality

From: Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus

  Univariate analysis
Variables HR 95% CI P value
MACE    
 Unadjusteda 5.69 3.05-10.62 <0.01
 Adjusted for demographic factorsb 3.81 2.01-7.24 <0.01
 Adjusted for demographic, cardiovascular risk factorsc 3.70 1.91-7.18 <0.01
 Adjusted for demographic, cardiovascular risk factors and eGFRd 2.85 1.15-7.03 0.02
Heart failure    
 Unadjusteda 7.21 2.70-19.25 <0.01
 Adjusted for demographic factorsb 4.98 1.80-13.83 <0.01
 Adjusted for demographic, cardiovascular risk factorsc 4.88 1.71-13.96 <0.01
 Adjusted for demographic, cardiovascular risk factors and eGFRd 4.88 1.12-21.31 0.03
Myocardial infarction    
 Unadjusteda 2.45 0.72-8.31 0.15
 Adjusted for demographic factorsb 1.70 0.48-5.99 0.41
 Adjusted for demographic, cardiovascular risk factorsc 1.34 0.36-5.04 0.67
 Adjusted for demographic, cardiovascular risk factors and eGFRd 0.84 0.12-6.17 0.87
Cardiovascular mortality    
 Unadjusteda 15.90 3.52-71.87 <0.01
 Adjusted for demographic factorsb 10.0 2.13-47.19 <0.01
 Adjusted for demographic, cardiovascular risk factorsc 9.14 1.92-43.60 <0.01
 Adjusted for demographic, cardiovascular risk factors and eGFRd 6.19 0.50-76.59 0.16
  1. Abbreviations as in Table 1; HR = hazard ratio.
  2. aAll models additionally adjusted for hs-TnI.
  3. bAdjusted for age and gender.
  4. cAdjusted for modelb and hypertension, hyperlipidemia, smoking history and coronary heart disease.
  5. dAdjusted for modelc and eGFR.
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Cardiovascular Diabetology

ISSN: 1475-2840