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Table 1 Baseline demographics of type 2 diabetes mellitus (T2DM) patients with and without elevated high sensitivity Troponin I (hs-TnI) and controls

From: Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus

Parameters

T2DM (n = 276)

Controls (n = 115)

P value

Elevated hs-TnI (n = 70)

Normal hs-TnI (n = 206)

P value

Age, years

64.4 ± 10.0

63.4 ± 7.9

0.29

68.6 ± 9.2

62.9 ± 9.9

<0.01

Male, % (n)

154 (56)

53 (61)

0.35

70 (49)

30 (21)

<0.01

Body mass index, kg/m2

25.5 ± 3.5

23.6 ± 3.4

<0.01

25.4 ± 3.5

25.6 ± 3.6

0.72

Current smoker, % (n)

33 (92)

6 (7)

<0.01

49 (34)

28 (58)

<0.01

Hypertension, % (n)

70 (194)

15 (17)

<0.01

89 (62)

132 (64)

<0.01

Hypercholesterolemia, % (n)

63 (174)

30 (26)

<0.01

70 (49)

61 (125)

0.10

Duration of DM, years

9.8 ± 7.6

--

--

10.2 ± 8.7

9.7 ± 7.3

0.67

CAD, % (n)

29 (113)

--

--

60 (42)

35 (71)

<0.01

Total cholesterol, mmol/L

4.6 ± 1.0

5.0 ± 0.9

<0.01

4.5 ± 1.1

4.7 ± 1.0

0.15

Triglycerides, mmol/L

1.6 ± 1.8

1.3 ± 0.8

<0.01

1.6 ± 1.1

1.6 ± 1.9

0.99

High density lipoprotein, mmol/L

1.3 ± 0.8

1.5 ± 0.4

<0.01

1.2 ± 0.4

1.3 ± 0.4

0.16

Low density lipoprotein, mmol/L

2.7 ± 0.8

3.0 ± 0.7

<0.01

2.6 ± 0.8

2.7 ± 0.8

0.55

eGFR, mL/min per 1.73 m2

81.8 ± 19.3

85.8 ± 14.1

0.03

72.0 ± 18.7

84.2 ± 18.7

<0.01

Fasting glucose, mmol/L

7.6 ± 2.3

5.1 ± 0.5

<0.01

7.6 ± 2.8

7.6 ± 2.1

0.96

HbA1c, %

7.8 ± 1.4

5.9 ± 0.4

<0.01

8.1 ± 1.7

7.7 ± 1.4

0.21

Medication

Insulin, % (n)

14 (38)

0 (0)

<0.01

19 (13)

12 (25)

0.13

Aspirin, % (n)

40 (109)

0 (0)

<0.01

56 (39)

34 (70)

<0.01

ACEI/ARB, % (n)

60 (166)

1 (1)

<0.01

77 (54)

54 (112)

<0.01

Statin, % (n)

42 (115)

2 (2)

<0.01

57 (40)

37 (75)

<0.01

  1. Abbreviation:
  2. ACEI = angiotensin converting enzyme inhibitor; ARB = angiotensin receptor blocker; CAD = coronary artery disease; eGFR = estimated glomerular filtration rate.