Differential association of visceral adipose tissue with coronary plaque characteristics in patients with and without diabetes mellitus

Table 6 Associations between adiposity measurements and vulnerable plaque

	Without DM (n = 334)				With DM (n = 122)
	Univariate		Multivariate		Univariate
	Odds ratio (95% CI)	p	Odds ratio (95% CI)	p	Odds ratio (95% CI)	p
Visceral adipose tissue:
T1	1				1
T2	3.28 (1.15–9.36)	0.03	2.32 (0.77–6.97)	0.13	1.26 (0.46–3.48)	0.65
T3	5.54 (2.02–15.18)	<0.01	3.17 (1.08–9.31)	0.04	0.84 (0.29–2.44)	0.74
Subcutaneous adipose tissue:
T1	1				1
T2	1.74 (0.82–3.68)	0.14	1.81 (0.81–4.05)	0.15	1.86 (0.67–5.13)	0.23
T3	0.67 (0.27–1.63)	0.37	1.14 (0.43–3.04)	0.8	0.82 (0.27–2.53)	0.73
Body mass index:
T1	1				1
T2	2.83 (1.19–6.74)	0.02	3.34 (1.30–8.58)	0.01	1.95 (0.68–5.62)	0.22
T3	1.99 (0.81–4.91)	0.13	1.99 (0.75–5.26)	0.17	1.33 (0.44–3.99)	0.62
Waist circumference:
T1	1				1
T2	3.84 (1.57–9.37)	<0.01	3.43 (1.34–8.77)	0.01	1.86 (0.67–5.13)	0.23
T3	1.97 (0.76–5.15)	0.17	1.77 (0.64–4.90)	0.27	0.82 (0.27–2.53)	0.73

The visceral adipose tissue area was divided into tertiles (T) as described in the Methods. The subcutaneous adipose tissue area was divided into tertiles as follows. In patients with DM, T1 ≤ 110 cm² (n = 40), 110 < T2 ≤ 155 cm² (n = 41), T3 > 155 cm² (n = 41). In patients without DM, T1 ≤ 92 cm² (n = 111), 92 < T2 ≤ 150 cm² (n = 112), T3 > 150 cm² (n = 111). The body mass index was divided into tertiles as follows. In patients with DM, T1 ≤ 22.72 kg/m² (n = 40), 22.72 < T2 ≤ 25.2 kg/m² (n = 41), T3 > 25.2 kg/m² (n = 41). In patients without DM, T1 ≤ 21.15 kg/m² (n = 111), 21.15 < T2 ≤ 24.06 kg/m² (n = 111), T3 > 24.06 kg/m² (n = 112). The waist circumference was divided into tertiles as follows. In patients with DM, T1 ≤ 81.5 cm (n = 40), 81.5 cm < T2 ≤ 91 cm (n = 41), T3 > 91 cm (n = 41). In patients without DM, T1 ≤ 77 cm (n = 111), 77 < T2 ≤ 86 cm (n = 112), T3 > 86 cm (n = 111). Multivariate analyses were adjusted for age, male sex, hypertension, dyslipidemia, and current smoking.
DM, diabetes mellitus; CI, confidence interval.

ISSN: 1475-2840