Skip to main content

Table 1 Cases (% of total) and number of subjects (% of cases) with any CVD, any coronary event, AMI, any cerebrovascular event, stroke, any peripheral event, ulcer/gangrene, and non-advanced and advanced DR according to eGFR and albuminuria category

From: Distribution of cardiovascular disease and retinopathy in patients with type 2 diabetes according to different classification systems for chronic kidney disease: a cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE) Italian multicenter study

Cases Any CVD
N A1 A2 A3 Total n A1 A2 A3 Total
G1 3,610 (22.9) 932 (5.9) 120 (0.8) 4,662 (29.6) G1 539 (14.9) 197 (21.1) 35 (29.2) 771 (16.5)
G2 6,255 (39.7) 1,653 (10.5) 244 (1.6) 8,152 (51.7) G2 1,218 (19.5) 480 (29.0) 82 (33.6) 1,780 (21.8)
G3a 1,253 (7.9) 562 (3.6) 136 (0.9) 1,951 (12.4) G3a 373 (29.8) 220 (39.2) 67 (49.3) 660 (33.8)
G3b 351 (2.2) 263 (1.7) 136 (0.9) 750 (4.8) G3b 129 (36.8) 135 (51.3) 61 (44.9) 325 (43.3)
G4 60 (0.4) 82 (0.5) 87 (0.6) 229 (1.5) G4 24 (40.0) 40 (48.8) 56 (64.4) 120 (52.4)
G5 9 (0.06) 5 (0.03) 15 (0.1) 29 (0.2) G5 2 (22.2) 3 (60.0) 4 (26.7) 9 (31.0)
Total 11,538 (73.2) 3,497 (22.2) 738 (4.7) 15,773 (100.0) Total 2,285 (19.8) 1,075 (30.7) 305 (41.3) 3,665 (23.2)
Any coronary event AMI
N A1 A2 A3 Total n A1 A2 A3 Total
G1 369 (10.2) 122 (13.1) 17 (14.2) 508 (10.9) G1 260 (7.2) 86 (9.2) 11 (9.2) 357 (7.7)
G2 835 (13.4) 298 (18.0) 43 (17.6) 1,176 (14.4) G2 614 (9.8) 218 (13.2) 31 (12.7) 863 (10.6)
G3a 264 (21.1) 136 (24.2) 36 (26.5) 436 (22.4) G3a 189 (15.1) 105 (18.7) 22 (16.2) 316 (16.2)
G3b 93 (26.5) 96 (36.5) 39 (28.7) 228 (30.4) G3b 68 (19.4) 73 (27.8) 31 (22.8) 172 (22.9)
G4 16 (26.7) 23 (28.1) 23 (26.4) 62 (27.1) G4 13 (21.7) 18 (22.0) 15 (17.2) 46 (20.1)
G5 1 (11.1) 1 (20.0) 3 (20.0) 5 (17.2) G5 1 (11.1) 1 (20.0) 2 (13.3) 4 (13.8)
Total 1,578 (13.7) 676 (19.3) 161 (21.8) 2,415 (15.3) Total 1,145 (9.9) 501 (14.3) 112 (15.2) 1,758 (11.2)
Any cerebrovascular event Stroke
N A1 A2 A3 Total n A1 A2 A3 Total
G1 167 (4.6) 62 (6.7) 12 (10.0) 241 (5.2) G1 57 (1.6) 23 (2.5) 7 (5.8) 87 (1.9)
G2 403 (6.4) 194 (11.7) 30 (12.3) 627 (7.7) G2 169 (2.7) 80 (4.8) 13 (5.3) 262 (3.2)
G3a 136 (10.9) 89 (15.8) 33 (24.3) 258 (13.2) G3a 52 (4.2) 28 (5.0) 13 (9.6) 93 (4.8)
G3b 48 (13.7) 53 (20.2) 23 (16.9) 124 (16.5) G3b 20 (5.7) 22 (8.4) 8 (5.9) 50 (6.7)
G4 11 (18.3) 19 (23.2) 22 (25.3) 52 (22.7) G4 3 (5.0) 8 (9.8) 10 (11.5) 21 (9.2)
G5 0 (0.0) 2 (40.0) 1 (6.7) 3 (10.3) G5 0 (0.0) 2 (40.0) 0 (0.0) 2 (6.9)
Total 765 (6.6) 419 (12.0) 121 (16.4) 1,305 (8.3) Total 301 (2.6) 163 (4.7) 51 (6.9) 515 (3.3)
Any peripheral event Ulcer/gangrene
N A1 A2 A3 Total n A1 A2 A3 Total
G1 99 (2.7) 51 (5.5) 11 (9.2) 161 (3.5) G1 53 (1.5) 38 (4.1) 9 (7.5) 100 (2.2)
G2 247 (4.0) 133 (8.1) 29 (11.9) 409 (5.0) G2 130 (2.1) 80 (4.8) 23 (9.4) 233 (2.9)
G3a 102 (8.1) 68 (12.1) 25 (18.4) 195 (10.0) G3a 53 (4.2) 42 (7.5) 17 (12.5) 112 (5.7)
G3b 23 (6.6) 48 (18.3) 24 (17.7) 95 (12.7) G3b 16 (4.6) 33 (12.6) 13 (9.6) 62 (8.3)
G4 3 (5.0) 8 (9.8) 19 (21.8) 30 (13.1) G4 2 (3.3) 6 (7.3) 13 (14.9) 21 (9.2)
G5 1 (11.1) 2 (40.0) 2 (13.3) 5 (17.2) G5 1 (11.1) 2 (40.0) 1 (6.7) 4 (13.8)
Total 475 (4.1) 310 (8.9) 110 (14.9) 895 (5.7) Total 255 (2.2) 201 (5.8) 76 (10.3) 532 (3.4)
Non-advanced DR Advanced DR
N A1 A2 A3 Total n A1 A2 A3 Total
G1 389 (10.8) 131 (14.1) 16 (13.3) 536 (11.5) G1 212 (5.9) 127 (13.6) 21 (17.5) 360 (7.7)
G2 657 (10.5) 258 (15.6) 37 (15.2) 952 (11.7) G2 425 (6.8) 229 (13.9) 63 (25.8) 717 (8.8)
G3a 165 (13.2) 105 (18.7) 30 (22.1) 300 (15.4) G3a 120 (9.6) 91 (16.2) 40 (29.4) 251 (12.9)
G3b 43 (12.3) 50 (19.0) 30 (22.1) 123 (16.4) G3b 47 (13.4) 56 (21.3) 35 (25.7) 138 (18.4)
G4 10 (16.7) 12 (14.6) 18 (20.7) 40 (17.5) G4 8 (13.3) 19 (23.2) 39 (44.8) 66 (28.8)
G5 0 (0.0) 1 (20.0) 5 (33.3) 6 (20.7) G5 0 (0.0) 1 (20.0) 7 (46.7) 8 (27.6)
Total 1,264 (11.0) 557 (15.9) 136 (18.4) 1,957 (12.4) Total 812 (7.0) 523 (15.0) 205 (27.8) 1,540 (9.8)
  1. CVD, cardiovascular disease; AMI, acute myocardial infarction; DR, diabetic retinopathy; eGFR, estimated glomerular filtration rate.
  2. eGFR (ml/min/1.73 m2): G1 = ≥90; G2 = 60-89; G3a = 45-59; G3b = 30-44; G4 = 15-29; G5 = <15; albuminuria: A1 = mormoalbuminuria; A2 = microalbuminuria; A3 = macroalbuminuria.