|
Cases
|
Any CVD
|
|---|
|
N
|
A1
|
A2
|
A3
|
Total
|
n
|
A1
|
A2
|
A3
|
Total
|
|---|
|
G1
|
3,610 (22.9)
|
932 (5.9)
|
120 (0.8)
|
4,662 (29.6)
|
G1
|
539 (14.9)
|
197 (21.1)
|
35 (29.2)
|
771 (16.5)
|
|
G2
|
6,255 (39.7)
|
1,653 (10.5)
|
244 (1.6)
|
8,152 (51.7)
|
G2
|
1,218 (19.5)
|
480 (29.0)
|
82 (33.6)
|
1,780 (21.8)
|
|
G3a
|
1,253 (7.9)
|
562 (3.6)
|
136 (0.9)
|
1,951 (12.4)
|
G3a
|
373 (29.8)
|
220 (39.2)
|
67 (49.3)
|
660 (33.8)
|
|
G3b
|
351 (2.2)
|
263 (1.7)
|
136 (0.9)
|
750 (4.8)
|
G3b
|
129 (36.8)
|
135 (51.3)
|
61 (44.9)
|
325 (43.3)
|
|
G4
|
60 (0.4)
|
82 (0.5)
|
87 (0.6)
|
229 (1.5)
|
G4
|
24 (40.0)
|
40 (48.8)
|
56 (64.4)
|
120 (52.4)
|
|
G5
|
9 (0.06)
|
5 (0.03)
|
15 (0.1)
|
29 (0.2)
|
G5
|
2 (22.2)
|
3 (60.0)
|
4 (26.7)
|
9 (31.0)
|
|
Total
|
11,538 (73.2)
|
3,497 (22.2)
|
738 (4.7)
|
15,773 (100.0)
|
Total
|
2,285 (19.8)
|
1,075 (30.7)
|
305 (41.3)
|
3,665 (23.2)
|
|
Any coronary event
|
AMI
|
|
N
|
A1
|
A2
|
A3
|
Total
|
n
|
A1
|
A2
|
A3
|
Total
|
|
G1
|
369 (10.2)
|
122 (13.1)
|
17 (14.2)
|
508 (10.9)
|
G1
|
260 (7.2)
|
86 (9.2)
|
11 (9.2)
|
357 (7.7)
|
|
G2
|
835 (13.4)
|
298 (18.0)
|
43 (17.6)
|
1,176 (14.4)
|
G2
|
614 (9.8)
|
218 (13.2)
|
31 (12.7)
|
863 (10.6)
|
|
G3a
|
264 (21.1)
|
136 (24.2)
|
36 (26.5)
|
436 (22.4)
|
G3a
|
189 (15.1)
|
105 (18.7)
|
22 (16.2)
|
316 (16.2)
|
|
G3b
|
93 (26.5)
|
96 (36.5)
|
39 (28.7)
|
228 (30.4)
|
G3b
|
68 (19.4)
|
73 (27.8)
|
31 (22.8)
|
172 (22.9)
|
|
G4
|
16 (26.7)
|
23 (28.1)
|
23 (26.4)
|
62 (27.1)
|
G4
|
13 (21.7)
|
18 (22.0)
|
15 (17.2)
|
46 (20.1)
|
|
G5
|
1 (11.1)
|
1 (20.0)
|
3 (20.0)
|
5 (17.2)
|
G5
|
1 (11.1)
|
1 (20.0)
|
2 (13.3)
|
4 (13.8)
|
|
Total
|
1,578 (13.7)
|
676 (19.3)
|
161 (21.8)
|
2,415 (15.3)
|
Total
|
1,145 (9.9)
|
501 (14.3)
|
112 (15.2)
|
1,758 (11.2)
|
|
Any cerebrovascular event
|
Stroke
|
|
N
|
A1
|
A2
|
A3
|
Total
|
n
|
A1
|
A2
|
A3
|
Total
|
|
G1
|
167 (4.6)
|
62 (6.7)
|
12 (10.0)
|
241 (5.2)
|
G1
|
57 (1.6)
|
23 (2.5)
|
7 (5.8)
|
87 (1.9)
|
|
G2
|
403 (6.4)
|
194 (11.7)
|
30 (12.3)
|
627 (7.7)
|
G2
|
169 (2.7)
|
80 (4.8)
|
13 (5.3)
|
262 (3.2)
|
|
G3a
|
136 (10.9)
|
89 (15.8)
|
33 (24.3)
|
258 (13.2)
|
G3a
|
52 (4.2)
|
28 (5.0)
|
13 (9.6)
|
93 (4.8)
|
|
G3b
|
48 (13.7)
|
53 (20.2)
|
23 (16.9)
|
124 (16.5)
|
G3b
|
20 (5.7)
|
22 (8.4)
|
8 (5.9)
|
50 (6.7)
|
|
G4
|
11 (18.3)
|
19 (23.2)
|
22 (25.3)
|
52 (22.7)
|
G4
|
3 (5.0)
|
8 (9.8)
|
10 (11.5)
|
21 (9.2)
|
|
G5
|
0 (0.0)
|
2 (40.0)
|
1 (6.7)
|
3 (10.3)
|
G5
|
0 (0.0)
|
2 (40.0)
|
0 (0.0)
|
2 (6.9)
|
|
Total
|
765 (6.6)
|
419 (12.0)
|
121 (16.4)
|
1,305 (8.3)
|
Total
|
301 (2.6)
|
163 (4.7)
|
51 (6.9)
|
515 (3.3)
|
|
Any peripheral event
|
Ulcer/gangrene
|
|
N
|
A1
|
A2
|
A3
|
Total
|
n
|
A1
|
A2
|
A3
|
Total
|
|
G1
|
99 (2.7)
|
51 (5.5)
|
11 (9.2)
|
161 (3.5)
|
G1
|
53 (1.5)
|
38 (4.1)
|
9 (7.5)
|
100 (2.2)
|
|
G2
|
247 (4.0)
|
133 (8.1)
|
29 (11.9)
|
409 (5.0)
|
G2
|
130 (2.1)
|
80 (4.8)
|
23 (9.4)
|
233 (2.9)
|
|
G3a
|
102 (8.1)
|
68 (12.1)
|
25 (18.4)
|
195 (10.0)
|
G3a
|
53 (4.2)
|
42 (7.5)
|
17 (12.5)
|
112 (5.7)
|
|
G3b
|
23 (6.6)
|
48 (18.3)
|
24 (17.7)
|
95 (12.7)
|
G3b
|
16 (4.6)
|
33 (12.6)
|
13 (9.6)
|
62 (8.3)
|
|
G4
|
3 (5.0)
|
8 (9.8)
|
19 (21.8)
|
30 (13.1)
|
G4
|
2 (3.3)
|
6 (7.3)
|
13 (14.9)
|
21 (9.2)
|
|
G5
|
1 (11.1)
|
2 (40.0)
|
2 (13.3)
|
5 (17.2)
|
G5
|
1 (11.1)
|
2 (40.0)
|
1 (6.7)
|
4 (13.8)
|
|
Total
|
475 (4.1)
|
310 (8.9)
|
110 (14.9)
|
895 (5.7)
|
Total
|
255 (2.2)
|
201 (5.8)
|
76 (10.3)
|
532 (3.4)
|
|
Non-advanced DR
|
Advanced DR
|
|
N
|
A1
|
A2
|
A3
|
Total
|
n
|
A1
|
A2
|
A3
|
Total
|
|
G1
|
389 (10.8)
|
131 (14.1)
|
16 (13.3)
|
536 (11.5)
|
G1
|
212 (5.9)
|
127 (13.6)
|
21 (17.5)
|
360 (7.7)
|
|
G2
|
657 (10.5)
|
258 (15.6)
|
37 (15.2)
|
952 (11.7)
|
G2
|
425 (6.8)
|
229 (13.9)
|
63 (25.8)
|
717 (8.8)
|
|
G3a
|
165 (13.2)
|
105 (18.7)
|
30 (22.1)
|
300 (15.4)
|
G3a
|
120 (9.6)
|
91 (16.2)
|
40 (29.4)
|
251 (12.9)
|
|
G3b
|
43 (12.3)
|
50 (19.0)
|
30 (22.1)
|
123 (16.4)
|
G3b
|
47 (13.4)
|
56 (21.3)
|
35 (25.7)
|
138 (18.4)
|
|
G4
|
10 (16.7)
|
12 (14.6)
|
18 (20.7)
|
40 (17.5)
|
G4
|
8 (13.3)
|
19 (23.2)
|
39 (44.8)
|
66 (28.8)
|
|
G5
|
0 (0.0)
|
1 (20.0)
|
5 (33.3)
|
6 (20.7)
|
G5
|
0 (0.0)
|
1 (20.0)
|
7 (46.7)
|
8 (27.6)
|
|
Total
|
1,264 (11.0)
|
557 (15.9)
|
136 (18.4)
|
1,957 (12.4)
|
Total
|
812 (7.0)
|
523 (15.0)
|
205 (27.8)
|
1,540 (9.8)
|
- CVD, cardiovascular disease; AMI, acute myocardial infarction; DR, diabetic retinopathy; eGFR, estimated glomerular filtration rate.
- eGFR (ml/min/1.73 m2): G1 = ≥90; G2 = 60-89; G3a = 45-59; G3b = 30-44; G4 = 15-29; G5 = <15; albuminuria: A1 = mormoalbuminuria; A2 = microalbuminuria; A3 = macroalbuminuria.
