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Figure 11 | Cardiovascular Diabetology

Figure 11

From: AGEs breaking and antioxidant treatment improves endothelium-dependent dilation without effect on flow-mediated remodeling of resistance arteries in old Zucker diabetic rats

Figure 11

Detection of advanced glycation end-products in mesenteric arteries: Detection of advanced glycation end-products (AGEs) using Western-blot analysis in mesenteric resistance arteries isolated from ZDF or LZ rats treated with ALT-711 (35 mg/kg per day), ALT-711 (35 mg/kg per day) + TEMPOL (B) or the solvent (control). In another series of experiments (C), rats were treated with ALT-711 (10 mg/kg per day) or ALT-711 (100 mg/kg per day). Molecular weight (MW) is shown along the blots. Values are presented as mean ± SEM, n = 10 rats per group (panel A and B). For panel C all the measurements are shown. *P < 0.05, ZDF versus LZ. #P < 0.05, treatment versus control.

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Cardiovascular Diabetology

ISSN: 1475-2840