Figure 7From: High glucose induces human endothelial dysfunction through an Axl-dependent mechanismAxl modulates expression of angiogenic factors in HG-induced angiogenesis. The results revealed that the Axl overexpression in HMEC-1Â s significantly reversed HG-induced VEGF and VEGFR2 expression (A and B). The Axl-shRNA-infected HMEC-1 cells showed significant additively decreased changes in the HG (40Â mM)-induced VEGF and VEGFR2 expression (C and D).Back to article page