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Table 1 General and biochemical parameters of lean and obese Zucker rats (12-14 weeks old)

From: Impaired dopamine D1 receptor-mediated vasorelaxation of mesenteric arteries in obese Zucker rats

 

Lean control

Obese control

Obese+ROG

Lean+HFD

Lean+STZ

Body weight (g)

273.83±5.37

439.64±7.34*

425.72±8.26

305.80±3.77*

222.79±3.38*

Plasma glucose (mmol/L)

5.86±0.17

8.88±0.48*

5.94±0.27#

6.22±0.15

>33.00*

Plasma insulin (ng/ml)

0.79±0.02

7.94±1.04*

2.97±0.44#

2.19±0.32*

0.46±0.06*

Mean blood pressure

118.91±1.85

138.26±3.62*

124.85±2.51#

120.59±2.39

129.66±1.51*

  1. Values are means ±SE; n=6. *P < 0.05 vs. lean control rats; #P < 0.05 vs. obese control rats.
  2. Obese rats were treated with rosiglitazone (ROG): 10mg/kg/day for 6 weeks; Lean rats were treated with high fat diet (HFD) and streptozotocin (STZ) for 4 weeks.
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Cardiovascular Diabetology

ISSN: 1475-2840