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Table 1 Demographic, clinical, lifestyle and genetic characteristics of the study participants at baseline by intervention groups

From: Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial

 

Total

MedDiet with EVOO

MedDiet nuts

Control group

(n = 7,161)

(n = 2,469)

(n = 2,363)

(n = 2,329)

Age (years)

67.0

± 6.2

67.0

± 6.2

66.7

± 6.1

67.3

± 6.3

BMI (Kg/m2)

30.0

± 3.8

29.9

± 3.7

29.7

± 3.8

30.2

± 4.0

Waist circumference (cm)

100.4

± 10.6

100.2

± 10.4

100.2

± 10.5

100.8

± 10.8

Female sex: n,%

4112

(57.4)

1448

(58.6)

1271

(53.8)

1393

(59.8)

Systolic blood pressure (mmHg)

149.4

± 20.8

148.5

± 20.8

149.6

± 20.4

150.1

± 21.1

Diastolic blood pressure (mmHg)

83.4

± 11.0

83.1

± 10.9

83.7

± 10.9

83.3

± 11.1

Heart rate (bpm)

71.4

± 11.2

71.4

± 11.1

71.2

± 11.1

71.6

± 11.3

Current smokers: n,%

1003

(14.0)

345

(14.0)

339

(14.3)

319

(13.7)

Type 2 diabetes: n,%

3462

(48.3)

1238

(50.1)

1096

(46.8)

1128

(48.4)

Hypertension: n,%

5928

(82.8)

2026

(82.1)

1954

(82.7)

1948

(83.6)

Dyslipidemia: n,%

5172

(72.2)

1766

(71.5)

1730

(73.2)

1676

(72.0)

FAIM2-rs7138803 (G > A) : n,%

        

GG

3019

(42.2)

1022

(41.4)

1000

(42.3)

997

(42.8)

GA

3235

(45.2)

1132

(45.8)

1062

(44.9)

1041

(44.7)

AA

907

(12.7)

315

(12.8)

301

(12.7)

291

(12.5)

Energy intake (kcal/d)

2274

± 606

2286

± 606

2317

± 610

2219

± 598

Total fat (% energy)

39.2

± 6.8

39.3

± 6.9

39.4

± 6.5

39.0

± 6.8

Saturated fat (% energy)

10.0

± 2.3

10.0

± 2.2

10.0

± 2.2

10.0

± 2.3

MUFA (% energy)

19.5

± 4.6

19.6

± 4.6

19.5

± 4.3

19.3

± 4.7

Proteins (% energy)

16.6

± 2.8

16.6

± 2.9

16.5

± 2.7

16.6

± 2.8

Carbohydrates (% energy)

41.9

± 7.1

41.7

± 7.2

41.5

± 7.0

42.3

± 7.2

Adherence to the MedDiet

8.6

± 2.0

8.7

± 2.0

8.7

± 2.0

8.4

± 2.1

Alcohol consumption (g/d)

8.4

± 14.2

8.6

± 14.4

9.2

± 15.0

7.5

± 13.1

Physical activity (MET-min/day)

231

± 239

232

± 231

247

± 246

215

± 241

  1. Values are mean ± SD for continuous variables and number (%) for categorical variables. BMI indicates body mass index.
  2. MUFA, Monounsaturated fatty acids; MedDiet, Mediterranean diet; EVOO, extra virgin olive oil.