Figure 6
From: Differential transendothelial transport of adiponectin complexes
HMW adiponectin uptake and function in skeletal muscle with exercise. A) Significantly greater concentrations of IR800-labeled HMW adiponectin were measured in the tricep, quadricep (quad), gastrocnemius (gastroc) and soleus muscles of mice that had run for 2 hours following tail vein infusion as compared to rested mice. Density calculated by direct tissue scan. B) Total tissue ceramide content (C16:0-C24:0) of oxidative muscles was significantly reduced by adiponectin with the greatest effect being observed in isolated soleus muscle. *p < 0.05, **p < 0.01 and ***p < 0.001 as compared to controls by two-tailed student’s t-test with unequal variance.