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Table 1 Effects of vildagliptin on heart weight

From: Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in rats

 

Vehicle

ISO

ISO-VL

Vehicle-VL

Number of rats

10

20

20

20

Body weight, g

237 ± 7

235 ± 10

234 ± 11

237 ± 6

Heart weight, g

0.76 ± 0.10

1.04 ± 0.11*

0.97 ± 0.10*#

0.75 ± 0.09

Heart weight/body weight × 103

3.21 ± 0.40

4.43 ± 039*

4.14 ± 0.29*#

3.16 ± 0.16

  1. ISO, isoproterenol; VL, vildagliptin. Values represent the mean ± SE. *p < 0.05 vs. vehicle and vehicle-VL; #p < 0.05 vs. ISO.